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Reversal of pradaxa anticoagulant9/5/2023 “The data now published in The Lancet show in an impressive manner how effective idarucizumab was for reversing Pradaxa® in healthy volunteers”, said Professor Jörg Kreuzer, Vice President Medicine Therapeutic Area Cardiovascular, Boehringer Ingelheim. Idarucizumab is an investigational drug, which has not been approved for clinical use, and further safety and efficacy testing will be required. Idarucizumab is the recommended International Nonproprietary Name (INN). Idarucizumab was well tolerated by the study participants. The reversal effect was sustained for more than 24 hours for all doses of 2g and above. After a five-minute infusion of idarucizumab, anticoagulation was immediately reversed back to baseline levels. The specific reversal agent was given two hours after the last dose of dabigatran etexilate, when dabigatran concentrations were at peak levels. In the healthy volunteer study now published in The Lancet, participants first received dabigatran etexilate and then idarucizumab. Idarucizumab was granted Breakthrough Therapy Designation by the US FDA and has recently been submitted for approval to the FDA, EMA and Health Canada. The data support the specific reversal agent as a highly targeted treatment option if reversal of the anticoagulant effect is needed, eg. The study showed that idarucizumab led to immediate, complete and sustained reversal of the anticoagulant effect of dabigatran etexilate. Results from a healthy volunteer study investigating the reversal of the anticoagulant effect of dabigatran etexilate (Pradaxa) by its specific reversal agent idarucizumab have been published recently in The Lancet.
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Flickr creative commons images9/5/2023 Unrestricted Stock – 2/3 A mix of stock photos and vectors, this site is entirely free and everything may be used for commercial purposes according to their licence agreement. Morgue offers HTML for posting the image, which I found quite helpful. I found about 1 in 7 images were CC, but many of these were still not available for commercial use. Morgue File – 1/3 Some great images, but you must click on each image individually to understand if it’s available under creative commons. – 3/3 With more than 17 million media files available and guaranteed creative commons, this is a great place to find quality images, though many strike me as non-professional.įlickr – 3/3 With a wealth of images and a simple advanced search for CC images, Flickr is a simple go-to for tapping into millions of images. Services like Pinterest thrive on quick visual bites and prove images ability to increase social engagement, plus they are easier for users to interact with than having to read words. Why is it important to use images in your content ? There are many reasons, but in nut shell: stunning images make your written content seem more interesting. It’s always important to understand the restriction on an image before using it, so please do double check images. Some sites supply exclusively creative commons or royalty free images, while other sites offered a mix of images which were free for commercial use with those that were not.
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Updating radeon drivers9/5/2023 Radeon cards can be updated manually, automatically or with the AMD Radeon update tool. Driver Support/ knowledgebase/ How to Do an AMD Radeon Driver UpdateĪMD drivers must be updated on Radeon graphics cards for proper functioning and performance.We are committed to resolve issues as quickly as possible and strongly encourage users to submit issues with AMD Software: Adrenalin Edition via the Bug Report Tool. We recommend users ensure all system updates are applied or paused before installing the driver, and that the “Factory Reset” option is unchecked during the AMD driver installation process. We have reproduced an issue that can occur in an extremely small number of instances if a PC update occurs during the installation of AMD Software: Adrenalin Edition, and we are actively investigating. Therefore, AMD recommends not using the Factory Reset option and ensuring Windows Update is not operating before installing a new driver. The company says the issue occurs when the user updates the driver while installing Windows updates, such as the recently released Moment 2 update. AMD has issued a warning to its graphics card customers that updating Radeon Software could cause severe issues and brick Windows installation in an "extremely small number of instances." The statement confirmed multiple user reports circulating the internet over the last few weeks.Īccording to AMD, using the "Factory Reset" option when updating Radeon Software causes the Inaccessible Boot Driver error, rendering the entire operating system completely bricked.
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Winmerge download for windows9/5/2023 WinMerge is an open-source comparing and merging tool for Windows. If you would like to try other differencing tools, check out the free alternatives below. Once the uninstallation wizard opens, confirm that you want to uninstall WinMerge and the software will be removed from your computer.Search for WinMerge on the list of installed applications, then click the “Uninstall” button.Type “Add or Remove Programs” in the Windows Search bar and hit the Enter button.If you are no longer interested in using WinMerge to compare and merge your files and folders, you can use the simple guide below to uninstall the application from your PC: Launch WinMerge to start comparing and merging different files and folders. Wait for the software installation to complete.
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Slack enterprise pricing9/4/2023 “Our company with a little less than 3000 people were quoted $1 million dollars per year (~$27 per person per month). “Unable to negotiate a discount, but we were able to be 'reimbursed' (with credit) for bot users that used 'real' accounts.” Our initial quote was $12/user/month, and we got them to drop it to $6.50/user/month.” If you have more unique circumstances, or are using Slack in a large company, you may be able to negotiate from 30-60% off, based on what others have shared: The best way to save is to use a Slack annual plan, which charges you upfront for the year but gives a ~17% discount.īut it doesn't hurt to ask. Here's what we've learned from over sixty teams who shared their Slack pricing: How to Get Slack Discountsįor most teams, Slack's default prices work out best. As long as your team doesn't have more than 10,000 messages, or doesn't need to view older messages, you're free to use Slack for free as long as you want.īut once you need to pay, what should your team expect to pay? The average team pays around $9.71 per user per month for Slack-though depending on your team's needs, you could pay a third less. Slack's free plan is generous-and nearly a fourth of the teams who shared their Slack pricing with Capiche still use Slack's free plan. That's how it slowly got adopted in companies from the bottom up, as smaller teams joined Slack, then got their wider division to start using it, and suddenly it was the way everyone talked at work. Any team can sign up for Slack and use all of its core features for free. Slack took over modern office communications partly because it's free to start.
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2022 cad9/4/2023 ACIS Reader/Writer library support for 2021 1.0.As usual we updated all the translators to guaranty the highest possible level of compatibility with other systems: The component, that provides the appropriate “converters” for the different CAD formats, is constantly improved.Īdditional file formats have been added to extend synergies with MI and open new market opportunities. This release continues VISI’s long tradition of bringing updated format support and continued enhancements and fixes to further improve the robustness and performance of 3D Modelling and Interoperability. We optimize the usability workflow, improving time reduction when performing modelling tasks. We added extra tools for inspection and design to improve our modelling performances and extending market opportunities. VISI 2022.0 contains several changes designed to simplify the software usage as well as removing the need for extra clicks providing an overall time reduction while improving productivity.
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Anydesk free for personal use9/4/2023 Meanwhile, if both devices have physical keyboards, users can remap the keys.Īdditionally, Chrome Remote Desktop includes Remote Support which provides users with a one-time code to access a desktop to fix any technical issues. We found it straightforward to access a 2015 iMac through an iPhone SE, however, the app lacked some essential keys such as Command, Control, and Option. It has an easy-to-use interface that offers multiple advantages such as compatibility with all Operating systems including macOS, Windows, and Android, and on both computers and phone devices.Ĭhrome Remote Desktop facilitates a simplified experience with cross-device compatibility. It can also be used for temporary, one-time access. You can use it to remotely access any computer also running the Chrome browser, whether the user is logged in or not, allowing you to control it without any interference. Chrome Remote Desktop is an extension that only works with the Chrome web browser.
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Download netbeans python9/3/2023 Under Oracle, NetBeans had to find some synergy with JDeveloper, a freeware IDE that has historically been a product of the company, by 2012 both IDEs were rebuilt around a shared codebase - the NetBeans Platform. In 2010, Sun (and thus NetBeans) was acquired by Oracle Corporation. Since then, the NetBeans community has continued to grow. Sun open-sourced the NetBeans IDE in June of the following year. In 1997, Roman Staněk formed a company around the project and produced commercial versions of the NetBeans IDE until it was bought by Sun Microsystems in 1999. NetBeans began in 1996 as Xelfi (word play on Delphi), a Java IDE student project under the guidance of the Faculty of Mathematics and Physics at Charles University in Prague.
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Before the Revamp, Kevin Conroy used a more upbeat tone when speaking publicly as Bruce Wayne. Bruce Wayne now speaks in roughly the same gruff tone as both himself and Batman.Almost all characters of the series have undergone changes in appearance, due to the streamlining of the DCAU (sometimes referred to as the "New Look" or “ Revamp”).Dick Grayson is now Nightwing, following a falling out with his mentor, only occasionally aiding the Dark Knight.Batgirl is now a full-time member of the team (and voiced by Tara Strong instead of Melissa Gilbert).Tim Drake has assumed the mantle of Robin.Notable Differences From Batman: The Animated Series Brooks Gardner as Waylon Jones/Killer Croc.Jeffrey Combs as Jonathan Crane/Scarecrow.Diane Pershing as Pamela Isley/Poison Ivy.Paul Williams as Oswald Cobblepot/Penguin.Arleen Sorkin as Harleen Quinzel/Harley Quinn.Adrienne Barbeau as Selina Kyle/Catwoman.Liane Schrimer as Detective Renee Montoya.Robert Costanzo as Detective Harvey Bullock.Bob Hastings as Commissioner James Gordon.2 Notable Differences From Batman: The Animated Series.
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Download marine corp 20229/3/2023 Some of the fighters include Americans who have volunteered, and Russian Legion, whom Zaal financially supports. The summit, through open discourse of opinions and discussion, aimed to further augment and improve the lives of the enlisted men and women currently serving in the Marine Corps. As the war in Ukraine enters its 16th month, Lance Zaal, founder of US Ghost Adventures, announces his fourth trip to the war zone June 6th to continue to support the men he trained and others he met along the way. The assistant commandant, former and current Sergeant Majors of the Marine Corps attended Sergeant Major of the Marine Corps summit. Green ret., former 18th Sergeant Major of the Marine Corps, far right, pose for a group photo at Marine Corps Base Quantico, V.A., May 3, 2022. Lee ret., former 13th Sergeant Major of the Marine Corps, second from right, and Sgt. Black, the current 19th Sergeant Major of the Marine Corps, third from right, Sgt. Smith, the Assistant Commandant of the Marine Corps, third from left, Sgt. McMichael ret., former 14th Sergeant Major of the Marine Corps, second from left, Gen. Estrada ret., former 15th Sergeant Major of the Marine Corps, far left, Sgt. |